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KMID : 0361020220650080467
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Korean Journal of Otolaryngology - Head and Neck Surgery
2022 Volume.65 No. 8 p.467 ~ p.471
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Recurrent Submandibular Gland Swelling Relieved by Antihistamine Medication: Is It Eosinophilic Sialodochitis?
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Kim Do-Hyung
Lee Sang-Eun
Han Kang-Min
Kim Bo-Hae
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Abstract
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Sialodochitis fibrinosa is a disease characterized by salivary duct obstruction. A 21-year-oldmale presented with a painful submandibular gland (SMG) swelling. Serum eosinophilia andWhartons’ duct dilatation with strong enhancement were observed on contrast CT. Core needlebiopsy (CNB) for SMG parenchyma revealed lymphocytic infiltration between dilated intralobularducts. In another case, a 39-year-old male complained of recurrent major salivaryglands swelling for ten years with an itching sensation on the overlying skin of the salivarygland. Enhancement of both SMG parenchyma, dilatation of both Wharton’s ducts and elevatedserum eosinophilia were observed on contrast CT study. CNB for SMG parenchyma revealedlymphocytic infiltration with many eosinophils around a markedly dilated interlobularduct. The recurrent SMG swelling in both cases were relieved by antihistamine medication,warranting suspicion that these cases might organ-specific eosinophilic disease. We dicussthese two cases with a literature review.
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KEYWORD
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Eosinophils, Histamine antagonists, Salivary gland diseases, Sialadenitis, Submandibular gland
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